The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2010
Filed:
Jan. 29, 2009
Ellen Baxter, Glenside, PA (US);
Christopher J. Creighton, San Diego, CA (US);
Chih Yung Ho, Lansdale, PA (US);
Yifang Huang, Lansdale, PA (US);
Tianbao LU, Churchville, PA (US);
Chi Luo, New Hope, PA (US);
Allen B. Reitz, Lansdale, PA (US);
Charles H. Reynolds, Lansdale, PA (US);
Tina Morgan Ross, Royerford, PA (US);
Ellen Sieber-mcmaster, Langhorne, PA (US);
Ellen Baxter, Glenside, PA (US);
Christopher J. Creighton, San Diego, CA (US);
Chih Yung Ho, Lansdale, PA (US);
Yifang Huang, Lansdale, PA (US);
Tianbao Lu, Churchville, PA (US);
Chi Luo, New Hope, PA (US);
Allen B. Reitz, Lansdale, PA (US);
Charles H. Reynolds, Lansdale, PA (US);
Tina Morgan Ross, Royerford, PA (US);
Ellen Sieber-McMaster, Langhorne, PA (US);
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention is directed to novel 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of β-secretase, also known as β-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.