The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2010

Filed:

Mar. 05, 2009
Applicants:

Tom Knapp, Carlsbad, CA (US);

Paul Negulescu, Solana Beach, CA (US);

Timothy Rink, Labande, MC;

Roger Tsien, La Jolla, CA (US);

Gregory Zlokarnik, La Jolla, CA (US);

Inventors:

Tom Knapp, Carlsbad, CA (US);

Paul Negulescu, Solana Beach, CA (US);

Timothy Rink, Labande, MC;

Roger Tsien, La Jolla, CA (US);

Gregory Zlokarnik, La Jolla, CA (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides a method for reducing undesirable light emission from a sample (e.g. a biochemical or cellular sample) with at least one photon producing agent and at least one collisional quencher. The present invention also provides a method for reducing undesirable light emission from a sample (e.g., a biochemical or cellular sample) with at least one photon producing agent and at least one quencher, such as an electronic quencher. The present invention also provides a system and method of screening test chemicals in fluorescent assays using photon reducing agents. The present invention also provides compositions, pharmaceutical compositions, and kits for practicing these methods.


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