The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2010
Filed:
Dec. 27, 2007
Peter Domenicali, Wilmington, MA (US);
Clifford Hoyt, Wellesley, MA (US);
Scott Determan, North Andover, MA (US);
Peter Miller, Cambridge, MA (US);
Peter Domenicali, Wilmington, MA (US);
Clifford Hoyt, Wellesley, MA (US);
Scott Determan, North Andover, MA (US);
Peter Miller, Cambridge, MA (US);
Cambridge Research Instrumentation, Inc., Woburn, MA (US);
Abstract
The invention provides for surface mapping of in-vivo imaging subjects using a single camera and a moveable stage on which a subject animal for in-vivo imaging is placed. Images are taken and the stage is moved by known amounts along the optical axis, and the heights of individual features on the subject are determined through analysis of focus, given the known stage displacement. Alternatively, height of sub-regions of the subject are determined through analysis of focus. A mesh or other surface can be constructed from individual features, to provide a surface map of the subject. Accuracy of 0.5 mm or better can be attained for mice and similarly sized subjects.