The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2010
Filed:
Nov. 21, 2007
Robert Eric Betzig, Okemos, MI (US);
Harald F. Hess, Ashburn, VA (US);
Robert Eric Betzig, Okemos, MI (US);
Harald F. Hess, Ashburn, VA (US);
Hestzig LLC, Ashburn, VA (US);
Abstract
First activation radiation is provided to a sample that includes phototransformable optical labels ('PTOLs') to activate a first subset of the PTOLs in the sample. First excitation radiation is provided to the first subset of PTOLs in the sample to excite at least some of the activated PTOLs, and radiation emitted from activated and excited PTOLs within the first subset of PTOLs is detecting with imaging optics. The first activation radiation is controlled such that the mean volume per activated PTOL in the first subset is greater than or approximately equal to a diffraction-limited resolution volume ('DLRV') of the imaging optics.