The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7781581 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 24, 2010

Filed:

Nov. 20, 2006
Applicants:

Tingman Wang, San Diego, CA (US);

John S. NG, Oak Park, CA (US);

Stephen E. Webber, San Diego, CA (US);

Inventors:

Tingman Wang, San Diego, CA (US);

John S. Ng, Oak Park, CA (US);

Stephen E. Webber, San Diego, CA (US);

Assignee:

Anadys Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for the preparation of 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-one which is a useful intermediate in the preparation of certain thiazolo[4,5-d]pyrimidine nucleosides. The process comprises halogenating 2,4-diaminopyrimidine to form 2,4-diamino-5-halo-pyrimidine and then cyclocondensing the 2,4-diamino-5-halo-pyrimidine to form 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-thione. The 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-thione is then oxidized to afford the 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-one.


Find Patent Forward Citations

Wang, Tingman. (2010). Process for the preparation of 5-amino-3h-thiazolo[4,5-d]pyrimidin-2-one (U.S. Patent No. 7781581). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7781581

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