The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2010

Filed:

Apr. 28, 2006
Applicants:

Gary Fanger, Southeast Mill Creek, WA (US);

Neil Fanger, Seattle, WA (US);

David John King, Belmont, CA (US);

Marc W. Retter, Carnation, WA (US);

Kenneth L. Rock, Chestnut Hill, MA (US);

Inventors:

Gary Fanger, Southeast Mill Creek, WA (US);

Neil Fanger, Seattle, WA (US);

David John King, Belmont, CA (US);

Marc W. Retter, Carnation, WA (US);

Kenneth L. Rock, Chestnut Hill, MA (US);

Assignees:

University of Massachusetts, Boston, MA (US);

Corixa Corporation, Seattle, WA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.


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