The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2010
Filed:
Aug. 30, 2006
Venkata Palle, Pune, IN;
Sarala Balachandran, Mumbai, IN;
Lalit Kumar Baregama, Kapasan, IN;
Saswati Chakladar, Delhi, IN;
Sarika Ramnani, Lucknow, IN;
Nagarajan Muthukamal, Tamil Nadu, IN;
Abhijit Ray, New Delhi, IN;
Sunanda G. Dastidar, New Delhi, IN;
Venkata Palle, Pune, IN;
Sarala Balachandran, Mumbai, IN;
Lalit Kumar Baregama, Kapasan, IN;
Saswati Chakladar, Delhi, IN;
Sarika Ramnani, Lucknow, IN;
Nagarajan Muthukamal, Tamil Nadu, IN;
Abhijit Ray, New Delhi, IN;
Sunanda G. Dastidar, New Delhi, IN;
Ranbaxy Laboratories Limited, New Delhi, IN;
Abstract
The present invention relates to isoxazoline derivatives of structure Ia, which can be used as selective inhibitors of phosphodiesterase (PDE) type IV. Compounds disclosed herein can be useful in the treatment of CNS disorders, AIDS, asthma, arthritis, bronchitis, chronic obstructive pulmonary disease (COPD), psoriasis, allergic rhinitis, shock, atopic dermatitis, Crohn's disease, adult respiratory distress syndrome (ARDS), eosinophilic granuloma, allergic conjunctivitis, osteoarthritis, ulcerative colitis and other inflammatory diseases especially in humans. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and their use as phosphodiesterase (PDE) type IV inhibitors.