The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2010

Filed:

Dec. 29, 2006
Applicants:

Adriaan Pieter Ijzermann, Haarlem, NL;

Reynier Tromp, Leiden, NL;

Inventors:

Adriaan Pieter Ijzermann, Haarlem, NL;

Reynier Tromp, Leiden, NL;

Assignees:

Gruenenthal GmbH, Aachen, DE;

Leiden University, Leiden, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/24 (2006.01); A61K 31/52 (2006.01); A61P 25/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Analogs or derivatives of nitrobenzylthioinosine corresponding to formula I: in which R represents an unsubstituted or mono- or polysubstituted phenyl, benzyl or heteroaryl group or a phenyl group condensed with heteroaryl, and R″ represents an unsubstituted or mono- or polysubstituted NH—C-alkyl, NH-aryl, NH-heteroaryl, NH—C-cycloalkyl, NH—C-alkyl-aryl, NH—C-alkyl-heteroaryl, N(C-alkyl), N(C-alkyl-aryl), N(C-alkyl-heteroaryl), piperidine, piperazine, morpholine or pyrrolidine group; pharmaceutical compositions comprising such analogs or derivatives, and the use of such analogs or derivatives for treating pain and/or various other diseases.


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