The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2010
Filed:
Dec. 06, 2004
Stanley L. Hazen, Pepper Pike, OH (US);
Michael Kinter, Shaker Heights, OH (US);
Marc S. Penn, Beachwood, OH (US);
Jonathan Smith, Shaker Heights, OH (US);
Lemin Zheng, Richmond Heights, OH (US);
Stanley L. Hazen, Pepper Pike, OH (US);
Michael Kinter, Shaker Heights, OH (US);
Marc S. Penn, Beachwood, OH (US);
Jonathan Smith, Shaker Heights, OH (US);
Lemin Zheng, Richmond Heights, OH (US);
The Cleveland Clinic Foundation, Cleveland, OH (US);
Abstract
Provided herein methods for determining whether a subject, particularly a human subject, is at risk of developing, having, or experiencing a complication of cardiovascular disease, and methods of treating subjects who are identified by the current methods of being at risk for cardiovascular disease. In one embodiment, the method comprises determining levels of one or more oxidized apolipoprotien A-I related biomolecules in a bodily sample from the subject. Also, provided are kits and reagents for use in the present methods. Also provided are methods for monitoring the status of cardiovascular disease in a subject or the effects of therapeutic agents on subjects with cardiovascular disease. Such method comprising determining levels of one or more oxidized apolipoprotein A-I related molecules in bodily samples taken from the subject over time or before and after therapy.