The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2010
Filed:
Dec. 22, 2004
Sina Bavari, Frederick, MD (US);
Rekha G. Panchal, Frederick, MD (US);
Ann Hermone, Frederick, MD (US);
Tam Nguyen, Gaithersburg, MD (US);
Rick Gussio, Frederick, MD (US);
Sina Bavari, Frederick, MD (US);
Rekha G. Panchal, Frederick, MD (US);
Ann Hermone, Frederick, MD (US);
Tam Nguyen, Gaithersburg, MD (US);
Rick Gussio, Frederick, MD (US);
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
Disclosed herein is a pharmacophore model for inhibiting anthrax lethal factor protease activity which comprises a first aromatic center A, a second aromatic center B, a first polar center C, a second polar center D, a third polar center E, and a neutral linker F. Also disclosed are small molecules fitting the pharmacophore model and compositions and methods of using thereof.