The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2010
Filed:
Mar. 29, 2007
Applicants:
Hongwei D. Yu, Huntington, WV (US);
Dongru Qiu, Huntington, WV (US);
Inventors:
Hongwei D. Yu, Huntington, WV (US);
Dongru Qiu, Huntington, WV (US);
Assignee:
Marshall University Research Corporation, Huntington, WV (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compositions and methods for detecting and controlling the conversion to mucoidy inare disclosed. The present invention provides for detecting the switch from nonmucoid to mucoid state ofby measuring mucE expression or MucE protein levels. The interaction between MucE and AlgW controls the switch to mucoidy in wild type. Also disclosed is an alginate biosynthesis heterologous expression system for use in screening candidate substances that inhibit conversion to mucoidy.