The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7777077 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 17, 2010

Filed:

Jan. 31, 2008
Applicants:

Seok-ki Choi, Palo Alto, CA (US);

Paul R. Fatheree, San Francisco, CA (US);

Ryan Hudson, Sunnyvale, CA (US);

Keith Jendza, San Francisco, CA (US);

Robert M. Mckinnell, Half Moon Bay, CA (US);

Vivek Sasikumar, Morrisville, NC (US);

Inventors:

Seok-Ki Choi, Palo Alto, CA (US);

Paul R. Fatheree, San Francisco, CA (US);

Ryan Hudson, Sunnyvale, CA (US);

Keith Jendza, San Francisco, CA (US);

Robert M. McKinnell, Half Moon Bay, CA (US);

Vivek Sasikumar, Morrisville, NC (US);

Assignee:

Theravance, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 239/00 (2006.01); C07D 257/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed to compounds of formula I: wherein Ar, r, R, X, and Rare as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds of formula I have ATreceptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and a process and intermediates for preparing such compounds.


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