The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2010

Filed:

May. 22, 2007
Applicants:

Penglie Zhang, Foster City, CA (US);

Andrew M. K. Pennell, San Francisco, CA (US);

John J. Kim Wright, Redwood City, CA (US);

Wei Chen, Fremont, CA (US);

Manmohan R. Leleti, Sunnyvale, CA (US);

Yandong LI, San Jose, CA (US);

Lianfa LI, Palo Alto, CA (US);

Yuan Xu, Fremont, CA (US);

Mark M. Gleason, Redwood City, CA (US);

Yibin Zeng, San Mateo, CA (US);

Kevin Lloyd Greenman, Burlingame, CA (US);

Inventors:

Penglie Zhang, Foster City, CA (US);

Andrew M. K. Pennell, San Francisco, CA (US);

John J. Kim Wright, Redwood City, CA (US);

Wei Chen, Fremont, CA (US);

Manmohan R. Leleti, Sunnyvale, CA (US);

Yandong Li, San Jose, CA (US);

Lianfa Li, Palo Alto, CA (US);

Yuan Xu, Fremont, CA (US);

Mark M. Gleason, Redwood City, CA (US);

Yibin Zeng, San Mateo, CA (US);

Kevin Lloyd Greenman, Burlingame, CA (US);

Assignee:

Chemocentryx, Inc., Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods are provided for the synthesis of 1-[4-(substituted phenyl)-piperazin-1-yl ] -2- [3-(1H-imidazol-2-yl)-pyrazolo [3,4-b]pyridin-1-yl]-ethanone compounds via construction of the imidazole portion onto the corresponding aldehyde or nitrile compounds.


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