The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2010

Filed:

Nov. 29, 2007
Applicants:

Tetsuya Kobayashi, Sunnyvale, CA (US);

Rao Kalla, Sunnyvale, CA (US);

Elfatih Elzein, Fremont, CA (US);

Jeff Zablocki, San Mateo, CA (US);

Brent Blackburn, Los Altos, CA (US);

Inventors:

Tetsuya Kobayashi, Sunnyvale, CA (US);

Rao Kalla, Sunnyvale, CA (US);

Elfatih Elzein, Fremont, CA (US);

Jeff Zablocki, San Mateo, CA (US);

Brent Blackburn, Los Altos, CA (US);

Assignee:

Gilead Palo Alto, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/519 (2006.01); A61P 25/28 (2006.01); A61P 25/24 (2006.01); A61P 3/04 (2006.01); A61P 37/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel compounds that are Aadenosine receptor antagonists having the structure of Formula I and to their use in treating mammals for various disease states, such as obesity, CNS disorders, including the 'movement disorders' (Parkinson's disease, Huntington's Chorea, and catelepsy), and cerebral ischemia, excitotoxicity, cognitive and physiological disorders, depression, ADHD, and drug addiction (alcohol, amphetamine, cannabinoids, cocaine, nicotine, and opioids) and to their use in the enhancement of immune response. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.


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