The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2010

Filed:

Dec. 06, 2004
Applicants:

Jason Alfred Dallwig, Eugene, OR (US);

David Carl Hagen, Eugene, OR (US);

Ching-ying Cheung, Eugene, OR (US);

Gerald Alan Thomas, Springfield, OR (US);

Stephen Yue, Eugene, OR (US);

Inventors:

Jason Alfred Dallwig, Eugene, OR (US);

David Carl Hagen, Eugene, OR (US);

Ching-Ying Cheung, Eugene, OR (US);

Gerald Alan Thomas, Springfield, OR (US);

Stephen Yue, Eugene, OR (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); C07D 215/12 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

Cyanine dye compounds having a substituted methine moiety that are nucleic acid stains, particularly for fluorescent staining of RNA, including compounds having the formula where Ris a C-Calkyl, sulfoalkyl, carboxyalkyl or C-Calkoxy; each Ris independently selected from the group consisting of H, C-Calkyl, C-Calkoxy, fused benzo, trifluoromethyl, amino, sulfo, carboxy and halogen, that is optionally further substituted; at least one of R, R, and Ris an alkyl, aryl, heteroaryl, cyclic, or heterocyclic moiety that is optionally substituted by alkyl, amino, aminoalkyl, carboxy, nitro, or halogen; and the remaining R, Ror Rare hydrogen; X is S, O, or Se; and D is a substituted or unsubstituted pyridinium, quinolinium or benzazolium moiety.


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