The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2010

Filed:

Oct. 25, 2005
Applicants:

Patrick A. Weiss, Huntsville, AL (US);

Violette Y. Weiss, Huntsville, AL (US);

Stefan Pitsch, Lausanne, CH;

Inventors:

Patrick A. Weiss, Huntsville, AL (US);

Violette Y. Weiss, Huntsville, AL (US);

Stefan Pitsch, Lausanne, CH;

Assignee:

Operon Biotechnologies, Inc., Huntsville, AL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/661 (2006.01); A61K 31/664 (2006.01); C07F 9/141 (2006.01); C07F 9/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

An amino or thiol linker building block for the synthesis of amino or thiol functionalized amino acids and generally of the following structure: is provided. Such building block may be introduced in the 5' end position of an amino acid under standard coupling conditions. Such building block allows in-line coupling control, 'trityl-on' purification, and solid support functionalization/derivatization. Such building block is a stable, solid compound and can therefore be easily handled. With the building block of the present invention, deprotection may be carried out under standard detritylation conditions.


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