The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2010

Filed:

Feb. 17, 2009
Applicants:

Bandi Parthasaradhi Reddy, Hyderabad, IN;

Kura Rathnakar Reddy, Hyderabad, IN;

Rapolu Raji Reddy, Hyderabad, IN;

Dasari Muralidhara Reddy, Hyderabad, IN;

Kesireddy Subash Chander Reddy, Hyderabad, IN;

Inventors:

Bandi Parthasaradhi Reddy, Hyderabad, IN;

Kura Rathnakar Reddy, Hyderabad, IN;

Rapolu Raji Reddy, Hyderabad, IN;

Dasari Muralidhara Reddy, Hyderabad, IN;

Kesireddy Subash Chander Reddy, Hyderabad, IN;

Assignee:

Hetero Drugs Limited, Hyderabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 209/00 (2006.01); C07C 211/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses novel and improved processes for preparation of sertraline hydrochloride crystalline form II. Thus, for example, sertraline free base is dissolved in isoamyl alcohol at 25-30° C., pH of the mass is adjusted to 2.0 with conc. hydrochloric acid (36%) at 25-30° C. and then stirred for 14 hours at 25-30° C. Filtered the solid and dried at 65° C. for 4 hours to give sertraline hydrochloride crystalline form II. The present invention also provides a novel process for preparation of sertraline hydrochloride crystalline form I.


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