The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2010
Filed:
Dec. 02, 2005
Jae-sun Kim, Gyeonggi-do, KR;
Jin Young Choi, Gyeonggi-do, KR;
Nam Ho Kim, Gyeonggi-do, KR;
Nam Kyu Lee, Gyeonggi-do, KR;
Jae-Sun Kim, Gyeonggi-do, KR;
Jin Young Choi, Gyeonggi-do, KR;
Nam Ho Kim, Gyeonggi-do, KR;
Nam Kyu Lee, Gyeonggi-do, KR;
SK Chemicals Co., Ltd., Gyeonggi-do, KR;
Abstract
The present invention relates to a method for optical resolution of amlodipines by using isopropanol solvent and optically active O,O'-dibenzoyl tartaric acid as chiral reagent. More particularly, the present invention relates to a method comprising (a) obtaining (R)- or (S)-amlodipine dibenzoyl tartrate salt or solvate thereof by reacting (R,S)-amlodipines with optically active O,O′-dibenzoyl tartaric acid in isopropanol solvent, and (b) treating the (R)- or (S)-amlodipine salt with a base, thus obtaining optically active amlodipine.