The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2010

Filed:

Jul. 21, 2008
Applicants:

Raymond Andersen, Vancouver, CA;

John Coleman, Vancouver, CA;

Dilip DE Silva, Vancouver, CA;

Fangming Kong, Vancouver, CA;

Edward Piers, Vancouver, CA;

Debra Wallace, Vancouver, CA;

Michel Roberge, Vancouver, CA;

Theresa Allen, Edmonton, CA;

Inventors:

Raymond Andersen, Vancouver, CA;

John Coleman, Vancouver, CA;

Dilip De Silva, Vancouver, CA;

Fangming Kong, Vancouver, CA;

Edward Piers, Vancouver, CA;

Debra Wallace, Vancouver, CA;

Michel Roberge, Vancouver, CA;

Theresa Allen, Edmonton, CA;

Assignee:

University of British Columbia, Vancouver, British Columbia, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R, R, R, R, R, R, R, R, R, and Rare as defined in the specification.


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