The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2010
Filed:
Dec. 18, 2008
Applicants:
Rong Zhang, Niskayuna, NY (US);
Faisal Ahmed Syud, Clifton Park, NY (US);
Jack Mathew Webster, Colonie, NY (US);
Inventors:
Rong Zhang, Niskayuna, NY (US);
Faisal Ahmed Syud, Clifton Park, NY (US);
Jack Mathew Webster, Colonie, NY (US);
Assignee:
General Electric Company, Niskayuna, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); C07K 14/00 (2006.01); C07K 5/10 (2006.01);
U.S. Cl.
CPC ...
Abstract
An isolated polypeptide, Z domain, derived from B domain ofprotein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of an engineered disulfide bridge between two natural or un-natural amino acids in the polypeptide is provided here. Also provided are methods of using the two-helix binders.