The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2010
Filed:
Apr. 20, 2006
Applicants:
Michael A. Firer, Ginot Shomron, IL;
Raisa Laptev, Ariel, IL;
Inventors:
Michael A. Firer, Ginot Shomron, IL;
Raisa Laptev, Ariel, IL;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); A61K 38/40 (2006.01); A61K 41/00 (2006.01); C07K 1/113 (2006.01); C07K 14/79 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for destroying harmful cells is provided, applicable in treating proliferative diseases. The cells are destroyed by a combined treatment with a chemiluminescent agent and with a ligand-photosensitizer conjugate. The chemiluminescent agent emits light on reacting with oxygen species present in situ, the conjugate binds to the cell through its ligand and is activated by the emitted light, thereby destroying the cell. The method is demonstrated on a conjugate of transferrin-hematoporphyrin, which destroys cancerous cells in the presence of luminol.