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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7771967 B1

PDFFull Text
Date of Patent:
Aug. 10, 2010

Filed:

Dec. 19, 2007

Nucleic acid encoding apolipoprotein e-i3

Applicants:

Yadong Huang, San Francisco, CA (US);

Qin Xu, Burlingame, CA (US);

Inventors:

Yadong Huang, San Francisco, CA (US);

Qin Xu, Burlingame, CA (US);

Assignee:

The J. David Gladstone Institutes, Irvine, CA (US);

Attorneys:

Paula A. Borden

Bozicevic, Field & Francis LLP

Primary Examiner:

Olga N Chernyshev

Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12P 21/04 (2006.01); C12P 1/00 (2006.01); C12P 19/34 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01); C07H 21/02 (2006.01); A01N 63/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides nucleic acids comprising a nucleotide sequence encoding an apolipoprotein E (apoE) splice variant, e.g., an unprocessed apoE, that retains intron 3; and vectors and host cells comprising same. The present invention further provides screening methods to identify agents that inhibit cleavage of intron-3 from the apoE splice variant. The present invention further provides methods of treating apoE-related neurological disorders, involving administering an agent that inhibits removal of intron-3 from a precursor apoE mRNA.

Find Patent Forward Citations

Huang, Yadong. (2010). Nucleic acid encoding apolipoprotein e-i3 (U.S. Patent No. 7771967). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7771967

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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