The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2010
Filed:
Oct. 08, 2004
Moriya Tsuji, New York, NY (US);
John Schmieg, New York, NY (US);
Richard Franck, Riverside, CT (US);
Yaoxing Huang, Brooklyn, NY (US);
Moriya Tsuji, New York, NY (US);
John Schmieg, New York, NY (US);
Richard Franck, Riverside, CT (US);
Yaoxing Huang, Brooklyn, NY (US);
New York University, New York, NY (US);
The Research Foundation of the City University of New York, New York, NY (US);
Aaron Diamond Aids Research Center, New York, NY (US);
Abstract
The present invention relates to methods and compositions for augmenting an immunogenicity of an antigen in a mammal, comprising administering said antigen together with an adjuvant composition that includes a synthetic glycolipid compound of Formula I, as described herein. According to the present invention, the use of a compound of Formula I as an adjuvant is attributed at least in part to the enhancement and/or extension of antigen-specific Th1-type responses, in particular, CD8+ T cell responses. The methods and compositions of the present invention can be useful for prophylaxis and treatment of various infectious and neoplastic diseases.