The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2010
Filed:
Aug. 29, 2006
Applicant:
Lisa Lynn Shafer, Stillwater, MN (US);
Inventor:
Lisa Lynn Shafer, Stillwater, MN (US);
Assignee:
Medtronic, Inc., Minneapolis, MN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Stimulation of one or more neurons of the sympathetic nervous system, including the splenic nerve, is provided to attenuate an immune response, including an inflammatory immune response. Devices such as pulse generators and drug pumps may be used to stimulate the sympathetic nervous system to attenuate an immune response. Systems optionally having one or more sensors and operator instructions may also be used. In specific examples, stimulation of the splenic nerve of pigs with a pulse generator is shown to be safe and effective in attenuating a lipopolysaccharide-induced immune response.