The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2010
Filed:
Jul. 08, 2004
Maria Gazdag, Budapest, HU;
Tibor Gizur, Budapest, HU;
Bela Hegedus, Budapest, HU;
Attila Szemzo, Budapest, HU;
Gabor Tarkanyi, Budaörs, HU;
Jozsef Törley, Budapest, HU;
Monika Babjak, Budapest, HU;
Maria Gazdag, Budapest, HU;
Tibor Gizur, Budapest, HU;
Bela Hegedus, Budapest, HU;
Attila Szemzo, Budapest, HU;
Gabor Tarkanyi, Budaörs, HU;
Jozsef Törley, Budapest, HU;
Monika Babjak, Budapest, HU;
Richter Gedeon Vegyeszeti Gyar RT., Budapest, HU;
Abstract
The invention relates to N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine (nateglinide) in the novel crystalline form 'G' and a process for the preparation thereof. A process for the preparation of chirally pure nateglinide by treating a lower alkyl ester thereof with a base to yield an alkali salt and liberating the product from said salt by proper addition of an acid, is also provided. Still another aspect of the invention is a process for the preparation of nateglinide in the crystalline form 'H' from other crystalline modifications of nateglinide.