The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2010
Filed:
Jun. 06, 2006
Stuart J Mickel, Lausen, CH;
Gottfried Sedelmeier, Schallstadt, DE;
Hans Hirt, Reinach, CH;
Frank Schäfer, Rheinfelden-Adelhausen, DE;
Michael Foulkes, Riehen, CH;
Walter Prikoszovich, Schönenbuch, CH;
Stuart J Mickel, Lausen, CH;
Gottfried Sedelmeier, Schallstadt, DE;
Hans Hirt, Reinach, CH;
Frank Schäfer, Rheinfelden-Adelhausen, DE;
Michael Foulkes, Riehen, CH;
Walter Prikoszovich, Schönenbuch, CH;
Novartis AG, Basel, CH;
Abstract
The present invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention provides a process for the manufacture of a compound of the formula III, wherein R, R, R, Rand PG are as defined in the specification, or a salt thereof. The manufacture comprises (preferably consists of) reacting a compound of the formula I, with a reagent able to transform hydroxy into X where X is for example a leaving group.