The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2010
Filed:
Apr. 18, 2005
Young-choon Moon, Belle Mead, NJ (US);
Liangxian Cao, Parlin, NJ (US);
Nadarajan Tamilarasu, Edison, NJ (US);
Hongyan Qi, Plainsboro, NJ (US);
Soongyu Choi, Skillman, NJ (US);
William Joseph Lennox, South Plainfield, NJ (US);
Donald Thomas Corson, Annandale, NJ (US);
Seongwoo Hwang, Edison, NJ (US);
Thomas Davis, South Orange, NJ (US);
Young-Choon Moon, Belle Mead, NJ (US);
Liangxian Cao, Parlin, NJ (US);
Nadarajan Tamilarasu, Edison, NJ (US);
Hongyan Qi, Plainsboro, NJ (US);
Soongyu Choi, Skillman, NJ (US);
William Joseph Lennox, South Plainfield, NJ (US);
Donald Thomas Corson, Annandale, NJ (US);
Seongwoo Hwang, Edison, NJ (US);
Thomas Davis, South Orange, NJ (US);
PTC Therapeutics, Inc., South Planfield, NJ (US);
Abstract
In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the treatment of solid tumor cancer, and in reducing plasma and/or tumor VEGF levels, are provided. In another aspect of the invention, methods are provided for the inhibition of VEGF production, the treatment of cancer, and the reduction of plasma and/or tumor VEGF levels, using the compounds of the invention.