The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2010
Filed:
Jun. 01, 2007
Per Artursson, Uppsala, SE;
Bjorn Erik Christensen, Trondheim, NO;
Magnus Koping-hoggard, Uppsala, SE;
Kjell Morten Varnum, Trondheim, NO;
Per Artursson, Uppsala, SE;
Bjorn Erik Christensen, Trondheim, NO;
Magnus Koping-Hoggard, Uppsala, SE;
Kjell Morten Varnum, Trondheim, NO;
FMC Biopolymer AS, Drammen, NO;
Abstract
The present invention concerns a composition comprising complexes of cationic chitosan oligomers derived from the cationic polysaccharide chitosan, wherein said cationic oligomers contain a weight fraction of less than 20% of oligomers with a Degree of Polymerization (DP)<10 in addition to a weight fraction of less than 20% with DP>50, and a nucleic acid. These compositions comprising well-defined cationic chitosan oligomers having a certain distribution of chain lengths, and nucleic acid are advantageous to achieve delivery of the nucleic acid into cells of a selected tissue, and to obtain in vivo expression of the desired molecules encoded for by the nucleic acid.