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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7767402 B1

PDFFull Text
Expired
Date of Patent:
Aug. 03, 2010

Filed:

Jun. 21, 2004

Methods and compositions for controlling appetite and modulating insulin sensitivity

Applicant:

Silvia Corvera, Westborough, MA (US);

Inventor:

Silvia Corvera, Westborough, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorneys:

Lahive & Cockfield, LLP

Debra J. Milasincic, Esq.

Richard B. Emmons

Primary Examiner:

Anand U Desai

Assistant Examiner:

Samuel Liu

Int. Cl.
CPC ...
G01N 33/566 (2006.01); G01N 33/567 (2006.01); C12N 5/0775 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention features methods of enhancing whole body insulin sensitivity by modulating the endoplasmic reticulum (ER) stress response pathway in adipose cells. In one aspect, the methods involve targeting chaperone proteins important in the ER stress response pathway, for example, BiP and ERO-1. Another aspect features targeting the upstream transcription factors (e.g., CHOP-1 and XBP-1) of the genes encoding the chaperone proteins (and/or other ER proteins). Screening assays for identification of modulators of these ER proteins and/or transcription factors are also featured.

Find Patent Forward Citations

Corvera, Silvia. (2010). Methods and compositions for controlling appetite and modulating insulin sensitivity (U.S. Patent No. 7767402). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7767402

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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