The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 2010

Filed:

Mar. 17, 2006
Applicants:

Martin Bachmann, Seuzach, CH;

Monika Bauer, Zurich, CH;

Klaus Dietmeier, Zurich, CH;

Nicole Schmitz, Urdorf, CH;

Stephan Utzinger, Schlieren, CH;

Inventors:

Martin Bachmann, Seuzach, CH;

Monika Bauer, Zurich, CH;

Klaus Dietmeier, Zurich, CH;

Nicole Schmitz, Urdorf, CH;

Stephan Utzinger, Schlieren, CH;

Assignee:

Cytos Biotechnology AG, Zurich-Schlieren, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/35 (2006.01); A61K 39/385 (2006.01); C12N 7/00 (2006.01); C07K 19/00 (2006.01); C07K 17/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides compositions comprising a virus-like particle (VLP) or a virus particle and at least one antigen, particularly at least one feline antigen, and more particularly at least one feline antigen that is a human allergen. In certain embodiments, the antigen is a Fel d1 antigen or a fragment thereof, covalently linked to the VLP. The invention also provides methods for producing the compositions. The compositions of the invention induce efficient immune responses, in particular antibody responses, in mammals, particularly humans. The compositions and methods of the invention are useful in the production of vaccines, in particular for the treatment and/or prevention of allergies to cat dander and other cat antigens and allergens.


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