The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2010
Filed:
Dec. 10, 2004
Carla Caccia, Cardano Al Campo, IT;
Laura Girola, Gerenzano, IT;
Petra Karin Kaltofen, Milan, IT;
Daniele Losi, Rovellasca, IT;
Patricia Salvati, Arese, IT;
Enrico Selva, Gropello Cairoli, IT;
Florian Thaler, Merano, IT;
Carla Caccia, Cardano Al Campo, IT;
Laura Girola, Gerenzano, IT;
Petra Karin Kaltofen, Milan, IT;
Daniele Losi, Rovellasca, IT;
Patricia Salvati, Arese, IT;
Enrico Selva, Gropello Cairoli, IT;
Florian Thaler, Merano, IT;
Newron Pharmaceuticals S.p.A., Bresso, IT;
Vicuron Pharmaceuticals Inc., Wilmington, DE (US);
Abstract
This invention is related to hydroxylamino derivatives of the general formula (I) wherein n is 0, 1 or 2; Rand R, independently of each other, are H, OH or OCH; Ris H or CH; Ris H, C-Cstraight or branched alkyl or, together with R, forms a five to seven-membered carbocyclic ring; and Rand R, independently of each other, are H or C-Cstraight or branched alkyl and the pharmaceutically acceptable salts or prodrug thereof, for the preparation of medicaments useful for the prevention, treatment and diagnosis of CNS degenerative disorders related to protein misfolding and/or misaggregation. The invention also relates to novel compounds included in formula (I), to a method for preparing said compounds and to pharmaceutical compositions containing them.