The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2010
Filed:
Apr. 19, 2007
Applicants:
Christian Wolf, Arlington, VA (US);
Shuanglong Liu, Arlington, VA (US);
Inventors:
Christian Wolf, Arlington, VA (US);
Shuanglong Liu, Arlington, VA (US);
Assignee:
Georgetown University, Washington, DC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/52 (2006.01); C07D 498/20 (2006.01);
U.S. Cl.
CPC ...
Abstract
One aspect of the invention relates to chiral bisoxazolidines and their use in asymmetric catalysis. The chiral bisoxazolidines are a novel class of compounds that is expected to find multiple applications, for example, in asymmetric synthesis. For example, a bisoxazolidine ligand enabled the catalytic enantioselective alkynylation and alkylation of a range of aromatic and aliphatic aldehydes, generating chiral propargylic alcohols and secondary alcohols in high yields and enantiomeric excess.