The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2010
Filed:
Mar. 04, 2004
Samuel Fournier Lockwood, Lake Linden, MI (US);
Sean O'malley, Honolulu, HI (US);
David G. Watumull, Honolulu, HI (US);
Laura M. Hix, San Francisco, CA (US);
Henry Jackson, Honolulu, HI (US);
Geoff Nadolski, Kaawa, HI (US);
Samuel Fournier Lockwood, Lake Linden, MI (US);
Sean O'Malley, Honolulu, HI (US);
David G. Watumull, Honolulu, HI (US);
Laura M. Hix, San Francisco, CA (US);
Henry Jackson, Honolulu, HI (US);
Geoff Nadolski, Kaawa, HI (US);
Cardax Pharmaceuticals, Inc., Aiea, HI (US);
Abstract
A method of controlling (e.g., influencing or affecting) connexin 43 expression in a subject may include administering to the subject an effective amount of a pharmaceutically acceptable formulation. In some embodiments, controlling connexin 43 expression in a subject may effectively treat cardiac arrhythmia and/or cancerous and pre-cancerous cells in a subject. The pharmaceutically acceptable formulation may include a synthetic analog or derivative of a carotenoid. The subject may be administered a carotenoid analog or derivative, either alone or in combination with another carotenoid analog or derivative, or co-antioxidant formulation. The carotenoid analog may include a conjugated polyene with between 7 to 14 double bonds. The conjugated polyene may include an acyclic alkene including at least one substituent and/or a cyclic ring including at least one substituent. In some embodiments, a carotenoid analog or derivative may include at least one substituent.