The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2010

Filed:

Aug. 18, 2006
Applicants:

John L. Buchanan, Newton, MA (US);

William H. Buckner, Kittery, ME (US);

Mario G. Cardozo, San Francisco, CA (US);

Erin F. Dimauro, Cambridge, MA (US);

Jiasheng Fu, Foster City, CA (US);

Xiaolin Hao, Foster City, CA (US);

Xian Yun Jiao, San Mateo, CA (US);

Frank Kayser, San Francisco, CA (US);

David J. Kopecky, San Francisco, CA (US);

Craig E. Masse, Cambridge, MA (US);

Susan A. Tomlinson, Cambridge, MA (US);

Ryan White, Somerville, MA (US);

Xiaotian Zhu, Newton, MA (US);

Inventors:

John L. Buchanan, Newton, MA (US);

William H. Buckner, Kittery, ME (US);

Mario G. Cardozo, San Francisco, CA (US);

Erin F. DiMauro, Cambridge, MA (US);

Jiasheng Fu, Foster City, CA (US);

Xiaolin Hao, Foster City, CA (US);

Xian Yun Jiao, San Mateo, CA (US);

Frank Kayser, San Francisco, CA (US);

David J. Kopecky, San Francisco, CA (US);

Craig E. Masse, Cambridge, MA (US);

Susan A. Tomlinson, Cambridge, MA (US);

Ryan White, Somerville, MA (US);

Xiaotian Zhu, Newton, MA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61K 31/496 (2006.01); A61P 35/00 (2006.01); C07D 231/56 (2006.01); A61K 31/416 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds of Formula I or a stereomer, a tautomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereof, pharmaceutical formulations containing the compounds, methods of treatments using the compounds, for example, protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders and methods of preparing medicaments comprising the compounds.


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