The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2010

Filed:

Jul. 29, 2004
Applicants:

Melwyn Abreo, Jamul, CA (US);

Daniel F. Harvey, San Diego, CA (US);

Mikhail A. Kondratenko, San Diego, CA (US);

Wenbao LI, San Diego, CA (US);

Rajender Kamboj, Burnaby, CA;

Vishnumurthy Kodumuru, Burnaby, CA;

Michael D. Winther, Vancouver, CA;

Heinz W. Gschwend, Santa Rosa, CA (US);

Nagasree Chakka, Burnaby, CA (US);

Shifeng Liu, Port Coquitlam, CA;

Serguei Sviridov, Burnaby, CA (US);

Shaoyi Sun, Vancouver, CA;

Inventors:

Melwyn Abreo, Jamul, CA (US);

Daniel F. Harvey, San Diego, CA (US);

Mikhail A. Kondratenko, San Diego, CA (US);

Wenbao Li, San Diego, CA (US);

Rajender Kamboj, Burnaby, CA;

Vishnumurthy Kodumuru, Burnaby, CA;

Michael D. Winther, Vancouver, CA;

Heinz W. Gschwend, Santa Rosa, CA (US);

Nagasree Chakka, Burnaby, CA (US);

Shifeng Liu, Port Coquitlam, CA;

Serguei Sviridov, Burnaby, CA (US);

Shaoyi Sun, Vancouver, CA;

Assignee:

Xenon Pharmaceuticals Inc., Burnaby, British Columbia, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 241/04 (2006.01); C07D 295/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein W, V, x, y, R, R, R, R, R, R, R, Ra, R, Ra, R, R, Rand Rare defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.


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