The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Mar. 08, 2006
Dieter Heindl, Paehl, DE;
Thomas Froehlich, Bichl, DE;
Heribert Maerz, Paehl, DE;
Monika Seller, Benediktbeuern, DE;
Dieter Heindl, Paehl, DE;
Thomas Froehlich, Bichl, DE;
Heribert Maerz, Paehl, DE;
Monika Seller, Benediktbeuern, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
The current invention restates substituted nitroindole nucleosides as both terminal as well as internal building blocks of labeled oligonucleotide probes for the detection, analysis and quantitation of nucleic acids. The substituent comprises a linker and a detectable group or a linker and a reactive group for post synthesis coupling. These modified nucleosides grant access to a wide application area. These new substituted nitroindole nucleosides can be used as labeling reagents for the facile preparation of, e.g., optimized hybridization probes, simple probes, TAQMAN-probes or molecular beacon probes.