The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Jul. 14, 2004
Manfred Schuster, Schrick, AT;
Gottfried Himmler, Vienna, AT;
Gunter Waxenecker, Mank, AT;
Geert C. Mudde, Breitenfurt, AT;
Manuela Loidl, Korneuburg, AT;
Gerda Redl, Rutzendorf, AT;
Hans Loibner, Vienna, AT;
Manfred Schuster, Schrick, AT;
Gottfried Himmler, Vienna, AT;
Gunter Waxenecker, Mank, AT;
Geert C. Mudde, Breitenfurt, AT;
Manuela Loidl, Korneuburg, AT;
Gerda Redl, Rutzendorf, AT;
Hans Loibner, Vienna, AT;
Greenovation Biotech GmbH, Freiburg, DE;
Meridian Biopharmaceuticals GmbH, Vienna, AT;
Abstract
The invention relates to a monoclonal antibody, or fragment of the antibody, that is derived from a parental monoclonal antibody, that recognizes the Lewis Y antigen, characterized in that the Fc region of the antibody, or fragment of the antibody, carries a bi-sected hybrid type N-glycosylation pattern and that the antibody shows at least 10 fold increased ADCC and at least 10% reduced CDC activity.