The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Sep. 27, 2004
Stanley Michael Roberts, Kirsbrook, GB;
Maria Gabriella Santoro, Avellino, IT;
Vasudev Jadhav, Chapel-en-le-Frith, GB;
Alan Michael Happe, Canterbury, GB;
Paul Evans, Liverpool, GB;
Nicolette Christa Ross, Chicago, IL (US);
Timothy James Snape, Ormskirk, GB;
Stanley Michael Roberts, Kirsbrook, GB;
Maria Gabriella Santoro, Avellino, IT;
Vasudev Jadhav, Chapel-en-le-Frith, GB;
Alan Michael Happe, Canterbury, GB;
Paul Evans, Liverpool, GB;
Nicolette Christa Ross, Chicago, IL (US);
Timothy James Snape, Ormskirk, GB;
Crawford Healthcare Holdings Limited, Cheshire, GB;
Abstract
A compound comprising a cyclopentanone, cyclopentenone, cyclohexanone or cyclohexenone group, wherein a first ring carbon atom carries an —SR substituent, R is a substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl, aralkenyl, or aralkynyl group that, optionally, includes at least one heteroatom in its carbon skeleton, the remaining available ring carbon atoms are optionally substituted, and said compound either: —(a) is more soluble in water at a temperature of 20-40° C.; (b) is less lipophilic; and/or, (c) has a greater therapeutic index; or; (d) is less soluble in water at a temperature of 20-40° C.; (e) is more lipophilic; and/or, (f) has a greater therapeutic index; than an equivalent cyclohex-2-en-1-one or cyclopent-2-en-1-one derivative in which a hydrogen atom replaces said —SR group.