The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Oct. 14, 2005
Karla Drescher, Dossenheim, DE;
Andreas Haupt, Schwetzingen, DE;
Liliane Unger, Ludwigshafen, DE;
Sean C. Turner, Mannheim, DE;
Wilfried Braje, Mannheim, DE;
Roland Grandel, Dossenheim, DE;
Karla Drescher, Dossenheim, DE;
Andreas Haupt, Schwetzingen, DE;
Liliane Unger, Ludwigshafen, DE;
Sean C. Turner, Mannheim, DE;
Wilfried Braje, Mannheim, DE;
Roland Grandel, Dossenheim, DE;
Abbott GmbH & Co. KG, Wiesbaden, DE;
Abstract
The present invention relates to 6-amino(aza)indane compound of the formula (I) Wherein Ar is phenyl or an aromatic 5- or 6-membered C-bound heteroaromatic radical, wherein Ar may carry 1 radical Rand wherein Ar may also carry I or 2 radicals R; X is N or CH; E is CRRor NR; Ris C-C-alkyl, C-C4-cycloalkyl, C-C-cycloalkylmethyl, C-C-alkenyl, fluorinated C-C-alkyl, fluorinated C-C-cycloalkyl, fluorinated C-C-cycloalkylmethyl, fluorinated C-C-alkenyl, formyl or C-C-alkylcarbonyl; Ris H or Rand Ror Rand Rtogether are (CH)with n being 1, 2, 3 or 4; Rand Reach independently are H, CH, CHF, CHFor CF; Ris H or C,-C4-alkyl; and the physiologically tolerated acid addition salts of these compounds. The invention also relates to pharmaceutical compositions comprising at least one compound of the formula (I) or a pharmaceutically acceptable salt thereof and to a method for treating a medical disorder susceptible to treatment with a dopamine D3 receptor ligand, said method comprising administering an effective amount of at least one compound of the formula (I) or a pharmaceutically acceptable salt thereof.