The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Sep. 07, 2006
Ravikumar Tadipartiii, Tamil Nadu, IN;
Venkatesan Parameswaran, Tamil Nadu, IN;
Rajib Barik, Tamil Nadu, IN;
Gaddam OM Reddy, Tamil Nadu, IN;
Pawan Aggarwal, Tamil Nadu, IN;
Sappanimuthu Thirunavukkarasu, Tamil Nadu, IN;
Sriram Rajagopal, Tamil Nadu, IN;
Ravikumar Tadipartiii, Tamil Nadu, IN;
Venkatesan Parameswaran, Tamil Nadu, IN;
Rajib Barik, Tamil Nadu, IN;
Gaddam Om Reddy, Tamil Nadu, IN;
Pawan Aggarwal, Tamil Nadu, IN;
Sappanimuthu Thirunavukkarasu, Tamil Nadu, IN;
Sriram Rajagopal, Tamil Nadu, IN;
Orchid Research Laboratories Ltd., Chennai, IN;
Abstract
The present invention relates to novel compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their metabolites and prodrugs thereof. The present invention more particularly relates to novel pyrimidine carboxamides of the general formula (I). Also included is a method of prophylaxis or treatment of a pain disorder, immunological diseases, inflammation, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; ischemic heart disease; atherosclerosis; cancer; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; adult respiratory distress syndrome (ARDS); psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; cachexia; asthma; bone resorption diseases; ischemia reperfusion injury; brain trauma; multiple sclerosis; sepsis; septic shock; toxic shock syndrome; fever, and myalgias due to infection in a mammal comprising administering an effective amount of a compound of formula (I) as described above.