The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7758868 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 20, 2010

Filed:

Dec. 24, 2007
Applicants:

Craig E. Cameron, State College, PA (US);

Christian Castro, State College, PA (US);

Jamie J. Arnold, State College, PA (US);

Inventors:

Craig E. Cameron, State College, PA (US);

Christian Castro, State College, PA (US);

Jamie J. Arnold, State College, PA (US);

Assignee:

The Penn State Research Foundation, University Park, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/13 (2006.01); C12N 7/00 (2006.01); C12N 7/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention encompasses compositions and methods relating to viral polymerases having one or more substitutions of different amino acids at conserved regions of the polymerase yields enzymes with varying rates and fidelity of replication. A universally applicable, polymerase-mechanism-based strategy for production of attenuated viruses and anti-viral vaccines is disclosed.


Find Patent Forward Citations

Cameron, Craig. (2010). Modified polymerases and attenuated viruses and methods of use thereof (U.S. Patent No. 7758868). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7758868

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