The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Mar. 21, 2006
Raghavan Rajagopalan, Beechwood, OH (US);
Samuel I. Achilefu, St. Louis, MO (US);
Joseph E. Bugaj, St. Charles, MO (US);
Richard D. Dorshow, St. Louis, MO (US);
Raghavan Rajagopalan, Beechwood, OH (US);
Samuel I. Achilefu, St. Louis, MO (US);
Joseph E. Bugaj, St. Charles, MO (US);
Richard D. Dorshow, St. Louis, MO (US);
Mallinckrodt Inc., Hazelwood, MO (US);
Abstract
The present invention discloses dye-sulfenate derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and free radicals at the lesion of interest.