The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7758852 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 20, 2010

Filed:

Apr. 02, 2003
Applicants:

Claudio Soto-jara, Friendswood, TX (US);

Claudia Pena-rossi, Geneva, CH;

Inventors:

Claudio Soto-Jara, Friendswood, TX (US);

Claudia Pena-Rossi, Geneva, CH;

Assignee:

Merck Serono SA, Coinsins, Vaud, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/52 (2006.01); A61K 45/00 (2006.01); A61K 39/00 (2006.01); A61K 51/00 (2006.01); A61K 38/00 (2006.01); A61K 39/385 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses peptides isolated from the extracellular domain of OX40 Ligand (OX40L) capable of binding OX40 Receptor (OX40R) and inhibiting OX40R-OX40L interaction. Such peptides, fusion proteins comprising them, as well as peptides and other molecules designed on their sequences, can be used as OX40R binding agents competing with natural OX40L for blocking OX40R-mediated cell signaling in the prophylaxis and/or treatment of diseases related to activated T cells.


Find Patent Forward Citations

Soto-Jara, Claudio. (2010). Ox40r binding agents (U.S. Patent No. 7758852). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7758852

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