The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2010

Filed:

Jan. 20, 2005
Applicants:

Kamal Azzaoui, Basel, CH;

Rochdi Bouhelal, Buschwiller, FR;

Peter Buehlmayer, Arlesheim, CH;

Danilo Guerini, Reinach, CH;

Manuel Koller, Schliern, CH;

Inventors:

Kamal Azzaoui, Basel, CH;

Rochdi Bouhelal, Buschwiller, FR;

Peter Buehlmayer, Arlesheim, CH;

Danilo Guerini, Reinach, CH;

Manuel Koller, Schliern, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/04 (2006.01); A01N 43/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to agonists of the S1P4 receptor, which are selective for the S1P4 receptor over one or more of the S1P1, S1P2, S1P3 or S1P5 receptors of at least 10 fold, in particular new indol-alanine derivatives of structure I, process for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them wherein


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