The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2010

Filed:

Sep. 05, 2008
Applicants:

Tomoharu Iino, Tsukuba, JP;

Noriaki Hashimoto, Tsukuba, JP;

Hiroshi Nakashima, Noda, JP;

Keiji Takahashi, Tsukuba, JP;

Teruyuki Nishimura, Ushiku, JP;

Jun-ichi Eiki, Tsuchiura, JP;

Inventors:

Tomoharu Iino, Tsukuba, JP;

Noriaki Hashimoto, Tsukuba, JP;

Hiroshi Nakashima, Noda, JP;

Keiji Takahashi, Tsukuba, JP;

Teruyuki Nishimura, Ushiku, JP;

Jun-ichi Eiki, Tsuchiura, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/425 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having glucokinase activating effects and being useful as treatments for diabetes, which are represented by the following formula (I): [wherein Xrepresents oxygen, etc., Xrepresents oxygen, etc., Rrepresents a group on Ring A such as alkylsulfonyl, etc., Rrepresents C3-7 cyclic alkyl optionally substituted with a halogen, etc., Rrepresents a substituent on Ring B such as lower alkyl, etc., formula (II):[Chemical Formula 1] represents 6- to 10-membered aryl, etc., and formula (III):[Formula 1] represents monocyclic or bicyclic heteroaryl optionally having on Ring B a substituent represented by Rabove, wherein the carbon atom of Ring B which is bonded to the nitrogen atom of the amide group of formula (I) forms a C═N bond with the nitrogen atom of the ring],as well as their pharmaceutically acceptable salts.


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