The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2010
Filed:
Aug. 11, 2006
Erin F. Dimauro, Cambridge, MA (US);
Jean E. Bemis, Arlington, MA (US);
Stuart C. Chaffee, Philadelphia, PA (US);
Ning Chen, Thousand Oaks, CA (US);
Essa HU, Camarillo, CA (US);
Roxanne Kunz, Santa Monica, CA (US);
Matthew W. Martin, Cambridge, MA (US);
David C. Mcgowan, Woluwe St. Pierre, BE;
Shannon Rumfelt, Camarillo, CA (US);
Erin F. Dimauro, Cambridge, MA (US);
Jean E. Bemis, Arlington, MA (US);
Stuart C. Chaffee, Philadelphia, PA (US);
Ning Chen, Thousand Oaks, CA (US);
Essa Hu, Camarillo, CA (US);
Roxanne Kunz, Santa Monica, CA (US);
Matthew W. Martin, Cambridge, MA (US);
David C. McGowan, Woluwe St. Pierre, BE;
Shannon Rumfelt, Camarillo, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including autoimmune disease and inflammation. In one embodiment, the compounds have a general Formula I wherein A, A, A, A, L, R, Rand Rare defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of the present invention, methods of use such as treatment of Lck and/or c-Kit kinase mediated diseases by administering the compounds of the invention, or compositions including one or more compounds of the invention, and intermediates and processes useful for the preparation of compounds of the present invention.