The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2010

Filed:

Oct. 15, 2008
Applicants:

Swen Hoelder, Constance, DE;

Karl Schoenafinger, Alzenau, DE;

David William Will, Kriftel, DE;

Hans Matter, Langenselbold, DE;

Gunter Muller, Sulzbach, DE;

Cecile Combeau, Fontenay aux Roses, FR;

Christine Delaisi, Saint Maur, FR;

Anke Steinmetz, Vitry sur Seine, FR;

Ingrid Sassoon, Villejuif, FR;

Inventors:

Swen Hoelder, Constance, DE;

Karl Schoenafinger, Alzenau, DE;

David William Will, Kriftel, DE;

Hans Matter, Langenselbold, DE;

Gunter Muller, Sulzbach, DE;

Cecile Combeau, Fontenay aux Roses, FR;

Christine Delaisi, Saint Maur, FR;

Anke Steinmetz, Vitry sur Seine, FR;

Ingrid Sassoon, Villejuif, FR;

Assignee:

Aventis Pharma S.A., Antony, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 31/5355 (2006.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds of the general formula (I), where the definition of the substituents A, B, D, E, Rand Rare detailed in the description, and the physiologically tolerated salts thereof, a process for the preparation of these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase CDK2 (cyclin-dependent kinase 2).


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