The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2010
Filed:
Nov. 10, 2006
Use of esters of unsaturated, physiologically active fatty acids as nutrient media for cell cultures
Albert Strube, Neuss, DE;
Claudia Scholz, Berlin, DE;
Jochen Seifert, Muehltal, DE;
Christophe Carite, Rilhac-Rancon, FR;
Christophe Sicre, Landorthe, FR;
Valerie Eychenne, Toulouse, FR;
Albert Strube, Neuss, DE;
Claudia Scholz, Berlin, DE;
Jochen Seifert, Muehltal, DE;
Christophe Carite, Rilhac-Rancon, FR;
Christophe Sicre, Landorthe, FR;
Valerie Eychenne, Toulouse, FR;
Cognis IP Management GmbH, Duesseldorf, DE;
Abstract
The disclosed invention relates to the use of esters of unsaturated, physiologically active fatty acids as nutrient media for cell cultivation and, more particularly, as a substitute for foetal bovine serum. In one aspect, the esters comprise more than 50 mol-% of physiologically active fatty acids containing 16 to 24 carbon atoms and 2 to 5 double bonds as the acid component and a lower Calcohol, preferably ethanol, or a sterol as ester component. In another aspect, the esters comprise a transesterification product of natural or synthetic oils or a mixture of such oils having greater than 50 mol-% of unsaturated, physiologically active fatty acids, based on the acyl group, and a lower Calcohol or a sterol. In a further aspect, the esters are used together with sterols, phospholipids and/or vegetable proteins or are liposomally encapsulated.