The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2010
Filed:
Jun. 19, 2009
Ellen Murphy, City Island, NY (US);
Emily Mara Braunstein, New York, NY (US);
Dorys Garcia-hand, Croton-on-Hudson, NY (US);
Annaliesa Sybil Anderson, Upper Saddle River, NJ (US);
Ingrid Lea Dodge, Cornwall, NY (US);
Eduardo Arturo Rojas, Briarcliff Manor, NY (US);
Ellen Murphy, City Island, NY (US);
Emily Mara Braunstein, New York, NY (US);
Dorys Garcia-Hand, Croton-on-Hudson, NY (US);
Annaliesa Sybil Anderson, Upper Saddle River, NJ (US);
Ingrid Lea Dodge, Cornwall, NY (US);
Eduardo Arturo Rojas, Briarcliff Manor, NY (US);
Wyeth LLC, Madison, NJ (US);
Abstract
The present invention relates to compositions and methods of use comprising peptidyl-prolyl isomerase (PPI) polypeptides of group C and G streptococci and polynucleotides encoding same. The invention also relates to immunogenic compositions comprising the PPI polypeptides and polynucleotides, as well as antibodies and antibody fragments that bind the PPI polypeptides. In addition, the invention relates to methods of inducing an immune response in a subject against beta hemolytic streptococci using the immunogenic compositions, as well as conferring passive immunity by administering a therapeutic antibody or antibody fragment.