The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2010

Filed:

Apr. 04, 2008
Applicants:

Siao-kun Wan Welch, Kalamazoo, MI (US);

Jay Gregory Calvert, Otsego, MI (US);

Michael K O'hara, Kalamazoo, MI (US);

Xuemei Cao, Scituate, MA (US);

Inventors:

Siao-Kun Wan Welch, Kalamazoo, MI (US);

Jay Gregory Calvert, Otsego, MI (US);

Michael K O'Hara, Kalamazoo, MI (US);

Xuemei Cao, Scituate, MA (US);

Assignee:

Pharmacia & Upjohn Company, LLC, Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/295 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides safe vaccines and methods of preparing such vaccines. The vaccines of the present invention contain at least two live mutant viruses of the same family or nucleic acid molecules encoding such viruses, wherein each of the two viruses or the encoding nucleic acids contains a mutation that confers a desirable phenotype and the mutations in the viruses reside in the same genomic site such that the mutant viruses cannot recombine with each other to eliminate the mutations.


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